acute pain; extreme suffering (mental or physical)
After the accidental death of their five-year old daughter, they were in a terrible anguish.
angustia (tightness, straitness, narrowness, distress, difficulty) (Latin)
anguish ~ ang (anger) + u + wish; You are in anger with someone, you wish him/her to suffer from pain and distress. Languish causes anguish.